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Inspiration
Glacial AugmentImmobilizing an enemy champion will cause 3 glacial rays that slow nearby enemies and reduce their damage to your allies.
Unsealed SpellbookSwap Summoner Spells while out of combat. Swapping to unique Summoner Spells will increase the rate at which you can make future swaps.
First StrikeWhen you initiate champion combat, deal 7% extra damage for 3 seconds and gain gold based on damage dealt.
Hextech FlashtraptionWhile Flash is on cooldown it is replaced by Hexflash . Hexflash : Channel, then blink to a new location.
Magical FootwearYou get free boots at 12 min but you cannot buy boots before then. Each takedown you get makes your boots come 45s sooner.
Cash BackGet some gold back when you purchase Legendary Items.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice. Upon reaching level 6, gain an Elixir of Force. Upon reaching level 9, gain an Elixir of Skill.
Time Warp TonicPotions grant some restoration immediately.
Biscuit DeliveryGain a free Biscuit every 2 min, until 6 min. Consuming or selling a Biscuit permanently increases your max health and restores health.
Cosmic Insight+ 18 Summoner Spell Haste + 10 Item Haste
Approach VelocityBonus MS towards nearby enemy champions that are movement impaired , increased for enemy champions that you impair.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you 1 Ability Haste . Gain bonus Adaptive Force at 5 and 10 stacks.
Precision
Absorb LifeKilling a target heals you.
TriumphTakedowns restore 5% of your missing health and grant an additional 20 gold.
Presence of MindRestore a small amount of mana or energy when damaging an enemy champion. Takedowns restore mana or energy.
Legend: AlacrityTakedowns on enemies grant permanent Attack Speed .
Legend: HasteTakedowns on enemies grant permanent Basic Ability Haste .
Legend: BloodlineTakedowns on enemies grant permanent Life Steal , up to a cap. Once the cap is reached, increase your max health. Weaker earlier but stronger later game than other Legend Runes.
Coup de GraceDeal more damage to low health enemy champions.
Cut DownDeal more damage to high health enemy champions.
Last StandDeal more damage to champions while you are low on health.
FlashTeleports you a short distance toward your cursor.
HealRestores Health and grants Move Speed to you and target allied champion.
FlashTeleports you a short distance toward your cursor.
IgniteDeals true damage over time to target enemy champion and reduces healing effects on them for the duration.
FlashTeleports you a short distance toward your cursor.
TeleportAfter a brief channel, become untargetable and travel to an allied unit. Upgrades into Unleashed Teleport, which significantly increases travel speed.
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Health Potion50gConsume to restore Health over time
Health Potion50gConsume to restore Health over time
Sorcerer's Shoes1,100gEnhances Move Speed and magic damage
Luden's Echo2,750gHigh burst damage, good against fragile foes›
Horizon Focus2,700gImmobilizing a champion causes lightning to strike them›
Shadowflame3,200g110 Ability Power 15 Magic Penetration Cinderbloom Magic and true damage Critically Strike enemies below 40% Health, dealing 20% increased damage.
Void Staff3,000gIncreases magic damage
Rabadon's Deathcap3,500gMassively increases Ability Power
Void Staff3,000gIncreases magic damage
Rabadon's Deathcap3,500gMassively increases Ability PowerNo matchup has reached 15games yet. A matchup's sample is split across every enemy champion in the lane, so it needs far more data than the overall stats do.
PKai'Sa's basic attacks stack Plasma, dealing increasing bonus magic damage. Allies' immobilizing effects help stack Plasma. Additionally, Kai'Sa's item purchases upgrade her basic spells to have more powerful properties.
QKai'Sa shoots a swarm of missiles that seek out nearby targets. Living Weapon: Icathian Rain is upgraded to shoot more missiles.
WKai'Sa shoots a long range missile, marking enemies with her passive. Living Weapon: Void Seeker is upgraded to apply more passive marks and reduce cooldown on champion hit.

Kai'Sa briefly increases her Move Speed, then increases her Attack Speed. Living Weapon: Supercharge is upgraded to briefly grant Invisibility.
RKai'Sa dashes near an enemy champion.